azintamide
- CAS NO.:1830-32-6
- Empirical Formula: C10H14ClN3OS
- Molecular Weight: 259.76
- MDL number: MFCD00867173
- EINECS: 2173842
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is azintamide?
Originator
Azintamide,Bristhar Laboratorios
Definition
ChEBI: Azintamide is an aryl sulfide.
Manufacturing Process
7.3 parts of 3-chloro-6-mercaptopyridazine are neutralised with 20 parts of 10% caustic soda solution, diluted with 60 parts of 50% ethanol, and heated to 60°C. 7.5 parts of chloroacetic acid diethyl amide dissolved in 20 parts of ethanol are added to this solution over a period of 10 min and the resulting mixture is heated to 60°C for 30 min. The reaction solution is then cooled, the resulting crystallisate is removed by suction, and the filtrate is extracted with ethyl acetate. The solvent is removed by evaporation and the concentration residue is combined with the crystallisate. After two recrystallisations from benzene, 11 parts of 3-chloro-pyridazine-6-mercaptoacetic acid diethyl amide, having a melting point of from 139° to 140°C are yielded.
Therapeutic Function
Choleretic
Properties of azintamide
Melting point: | 97-98° |
Boiling point: | 435.3±40.0 °C(Predicted) |
Density | 1.27±0.1 g/cm3(Predicted) |
pka | -0.49±0.10(Predicted) |
Safety information for azintamide
Computed Descriptors for azintamide
Related products of tetrahydrofuran
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