Azido-PEG1-CH2CO2H
- CAS NO.:79598-48-4
- Empirical Formula: C4H7N3O3
- Molecular Weight: 145.11668
- MDL number: MFCD24452584
- Update Date: 2024-10-23 13:36:13
What is Azido-PEG1-CH2CO2H?
Description
Azido-PEG1-CH2CO2H is a PEG linker containing an azide group with a terminal carboxylic acid. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
The Uses of Azido-PEG1-CH2CO2H
2-(2-Azidoethoxy)acetic Acid is an intermediate in the synthesis of 3-O-Desethyl-5-O-desmethyl Amlodipine (D291305). 3-O-Desethyl-5-O-desmethyl Amlodipine is an impurity of Amlodipine (A633495), which is a dihydropyridine calcium channel blocker.
Properties of Azido-PEG1-CH2CO2H
solubility | Soluble in Water, DCM |
form | Liquid |
color | Colorless to light yellow |
Safety information for Azido-PEG1-CH2CO2H
Computed Descriptors for Azido-PEG1-CH2CO2H
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