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HomeProduct name listazafenidin

azafenidin

azafenidin Structural

What is azafenidin?

The Uses of azafenidin

Azafenidin is a weed controlling herbicide used in various crops.

The Uses of azafenidin

Herbicide.

Definition

ChEBI: Azafenidin is a triazolopyridine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one which is substituted at position 2 by a 2,4-dichloro-5-(prop-2-yn-1-yloxy)phenyl group. A protoporphyrinogen oxidase inhibitor, it is used as a herbicide to control weeds in fruit crops such as pineapple, citrus, melons, and grapes. Not approved for use within the European Union. It has a role as an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor. It is a triazolopyridine, a terminal acetylenic compound and a dichlorobenzene.

Metabolic pathway

A common degradation reaction of azafenidin in light, plants and soil is O-dealkylation, and interesting minor reactions in soil are the subsequent methylation of the O-dealkylated degradation product and the reduction of the propynyl group under anaerobic conditions. In soil and light, azafenidin is also readily split to form the triazolinone heterocycle. Azafenidin is readily metabolized in rats and lactating goats through O-dealkylation, hydroxylation of the triazolinone ring in several positions, and glucuronide and sulfate conjugation.

Properties of azafenidin

Melting point: 168-168.5°
Boiling point: 468.9±55.0 °C(Predicted)
Density  1.43±0.1 g/cm3(Predicted)
solubility  DMSO (Slightly), Methanol (Slightly)
pka 2.45±0.20(Predicted)
form  Solid
color  Brown to Dark Brown
EPA Substance Registry System Azafeniden (68049-83-2)

Safety information for azafenidin

Computed Descriptors for azafenidin

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