AMITRIPTYLINE METABOLITE (+/-)-
Synonym(s):(±)-(E)-5-[3-(Dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol
- CAS NO.:64520-05-4
- Empirical Formula: C20H23NO
- Molecular Weight: 293.4
- MDL number: MFCD00069200
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:41
What is AMITRIPTYLINE METABOLITE (+/-)-?
The Uses of AMITRIPTYLINE METABOLITE (+/-)-
(5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).
What are the applications of Application
Amitriptyline metabolite, (±)-E-10-hydroxylated- is a metabolite of amitriptyline
Definition
ChEBI: E-10-Hydroxyamitriptyline is an organic tricyclic compound.
Biochem/physiol Actions
Metabolite of amitriptyline, tricyclic antidepressant; chromatographic standard.
Properties of AMITRIPTYLINE METABOLITE (+/-)-
Melting point: | 97-99 °C |
Boiling point: | 453.3±45.0 °C(Predicted) |
Density | 1.151±0.06 g/cm3(Predicted) |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | 0.1 M HCl: soluble |
form | solid |
pka | 13.89±0.20(Predicted) |
color | white |
Stability: | Hygroscopic |
EPA Substance Registry System | 5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)- (64520-05-4) |
Safety information for AMITRIPTYLINE METABOLITE (+/-)-
Computed Descriptors for AMITRIPTYLINE METABOLITE (+/-)-
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
NORTRIPTYLINE
1,1-DI(O-TOLYL)ETHYLENE
10,11-DIHYDRO-5 H-DIBENZO[A,D]CYCLOHEPTENE
cyproheptadine 10,11-epoxide
Amitriptyline
AMITRIPTYLINE METABOLITE (+/-)-
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