AMITRIPTYLINE METABOLITE (+/-)-
Synonym(s):(±)-(E)-5-[3-(Dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol
- CAS NO.：64520-05-4
- Empirical Formula: C20H23NO
- Molecular Weight: 293.4
- MDL number: MFCD00069200
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:41
What is AMITRIPTYLINE METABOLITE (+/-)-?
The Uses of AMITRIPTYLINE METABOLITE (+/-)-
(5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).
What are the applications of Application
Amitriptyline metabolite, (±)-E-10-hydroxylated- is a metabolite of amitriptyline
Definition
ChEBI: E-10-Hydroxyamitriptyline is an organic tricyclic compound.
Biochem/physiol Actions
Metabolite of amitriptyline, tricyclic antidepressant; chromatographic standard.
Properties of AMITRIPTYLINE METABOLITE (+/-)-
| Melting point: | 97-99 °C |
| Boiling point: | 453.3±45.0 °C(Predicted) |
| Density | 1.151±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | 0.1 M HCl: soluble |
| form | solid |
| pka | 13.89±0.20(Predicted) |
| color | white |
| Stability: | Hygroscopic |
| EPA Substance Registry System | 5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)- (64520-05-4) |
Safety information for AMITRIPTYLINE METABOLITE (+/-)-
Computed Descriptors for AMITRIPTYLINE METABOLITE (+/-)-
New Products
(R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin I Tubulysin F 4-(Benzyloxy)-3-bromophenylacetic Acid 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 3,6-Dihydro-2H-pyran-4-carbonitrile tetrahydro-4-methyl-2H-pyran (R)-1-BOC-3-FLUORO PYRROLIDINE Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- 1-(4-amino-2- methylbenzoyl)-7- chloro-3,4-dihydro- 1H-benzo[b] azepin-5(2H)-one 3-(4-Chloro-butyryl) -1H-indole-5- carbonitrile 2,3-dichloro-6- nitrobenzonitrile 2-Methyl-4- nitro Benzoic acid 2-(2-Formylphenoxy) acetic acid 5-Piperazin-1-yl- benzofuran-2- carboxylic acid ethyl ester. HCl 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acid 7-Methoxyquinoline-4-carbonitrile Methyl (2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoate (R)-methyl 2-isocyano-3-(tritylthio)propanoate (R)-methyl 2-formamido-3-(tritylthio)propanoate BETAMETHASONE DIPROPIONATE EP IMPURITY H HALOPERIDOL N-OXIDE Mycophenolate Mofetil EP Impurity E / Mycophenolic Acid Methyl EsterRelated products of tetrahydrofuran
![10,11-DIHYDRO-5 H-DIBENZO[A,D]CYCLOHEPTENE](https://img.chemicalbook.in/CAS/GIF/833-48-7.gif)
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