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HomeProduct name listAMITRIPTYLINE METABOLITE (+/-)-

AMITRIPTYLINE METABOLITE (+/-)-

Synonym(s):(±)-(E)-5-[3-(Dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol

AMITRIPTYLINE METABOLITE  (+/-)- Structural

What is AMITRIPTYLINE METABOLITE (+/-)-?

The Uses of AMITRIPTYLINE METABOLITE (+/-)-

(5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).

What are the applications of Application

Amitriptyline metabolite, (±)-E-10-hydroxylated- is a metabolite of amitriptyline

Definition

ChEBI: E-10-Hydroxyamitriptyline is an organic tricyclic compound.

Biochem/physiol Actions

Metabolite of amitriptyline, tricyclic antidepressant; chromatographic standard.

Properties of AMITRIPTYLINE METABOLITE (+/-)-

Melting point: 97-99 °C
Boiling point: 453.3±45.0 °C(Predicted)
Density  1.151±0.06 g/cm3(Predicted)
storage temp.  Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility  0.1 M HCl: soluble
form  solid
pka 13.89±0.20(Predicted)
color  white
Stability: Hygroscopic
EPA Substance Registry System 5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)- (64520-05-4)

Safety information for AMITRIPTYLINE METABOLITE (+/-)-

Computed Descriptors for AMITRIPTYLINE METABOLITE (+/-)-

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