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HomeProduct name listAMAROGENTIN

AMAROGENTIN

AMAROGENTIN Structural

What is AMAROGENTIN?

Chemical properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dry roots and rhizomes of Gentiana Gentiana scabra Bge.

The Uses of AMAROGENTIN

Amarogentin has the functions of protecting liver and gallbladder, inhibiting bacteria and diuretic.

Definition

ChEBI: Amarogentin is a secoiridoid glycoside that consists of (4aS,5R,6R)-5-ethenyl-6-hydroxy-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one having a 2-O-[(3,3',5-trihydroxybiphenyl-2-yl)carbonyl]-beta-D-glucopyranosyl group attached at position 6 via a glycosidic linkage. It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a metabolite. It is a secoiridoid glycoside and a monosaccharide derivative.

Properties of AMAROGENTIN

Melting point: 229-230° (monohydrate)
Boiling point: 928.5±65.0 °C(Predicted)
alpha  D20 -116.6° (methanol)
Density  1.59±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMF: 1 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.1 mg/ml
form  A crystalline solid
pka 7.42±0.40(Predicted)
color  White to off-white

Safety information for AMAROGENTIN

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for AMAROGENTIN

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