AMAROGENTIN
- CAS NO.:21018-84-8
- Empirical Formula: C29H30O13
- Molecular Weight: 586.54
- MDL number: MFCD30541334
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-12 15:22:20
What is AMAROGENTIN?
Chemical properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dry roots and rhizomes of Gentiana Gentiana scabra Bge.
The Uses of AMAROGENTIN
Amarogentin has the functions of protecting liver and gallbladder, inhibiting bacteria and diuretic.
Definition
ChEBI: Amarogentin is a secoiridoid glycoside that consists of (4aS,5R,6R)-5-ethenyl-6-hydroxy-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one having a 2-O-[(3,3',5-trihydroxybiphenyl-2-yl)carbonyl]-beta-D-glucopyranosyl group attached at position 6 via a glycosidic linkage. It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a metabolite. It is a secoiridoid glycoside and a monosaccharide derivative.
Properties of AMAROGENTIN
Melting point: | 229-230° (monohydrate) |
Boiling point: | 928.5±65.0 °C(Predicted) |
alpha | D20 -116.6° (methanol) |
Density | 1.59±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMF: 1 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.1 mg/ml |
form | A crystalline solid |
pka | 7.42±0.40(Predicted) |
color | White to off-white |
Safety information for AMAROGENTIN
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for AMAROGENTIN
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-(dimethylamino)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one Iminostilbene 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN Diclofenac Sodium SODIUM VALPROATE Racecadotril XANTHAN GUM 5-Fluoro-2-iodo-3-methylphenol 4-(Cyanomethyl)-1-piperidineacetamide 6-Bromo-2-iodo-4-methyl-3-pyridinamine 5-Amino-3-bromo-2-chlorobenzeneacetic acidRelated products of tetrahydrofuran
1α-(β-D-Glucopyranosyloxy)-1,4a,5,6,7,7aα-hexahydro-4aα-hydroxy-7α-methyl-5-oxocyclopenta[c]pyran-4-carboxylic acid methyl ester
Valtrate
2-Ethoxy-3,4-dihydro-4-methyl-2H-pyran
3-Hydroxy-4-methylbenzoic acid
BIPHENYL-3-CARBOXYLIC ACID ETHYL ESTER
AMAROGENTIN
Methyl 4-phenylbenzoate
3,5-Dihydroxy-4-methylbenzoic acid
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