alpha, oMega-Dipropionic acid hexaethylene glycol
- CAS NO.：94376-75-7
- Empirical Formula: C18H34O11
- Molecular Weight: 426.46
- MDL number: MFCD11041125
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:54:57
What is alpha, oMega-Dipropionic acid hexaethylene glycol?
Description
Bis-PEG7-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Biological Activity
Bis-PEG7-acid is a PROTAC linker belonging to the PEG class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).
Properties of alpha, oMega-Dipropionic acid hexaethylene glycol
| form | Viscous Liquid |
| color | Colorless to light yellow |
Safety information for alpha, oMega-Dipropionic acid hexaethylene glycol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for alpha, oMega-Dipropionic acid hexaethylene glycol
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