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HomeProduct name listalpha, oMega-Dipropionic acid hexaethylene glycol

alpha, oMega-Dipropionic acid hexaethylene glycol

alpha, oMega-Dipropionic acid hexaethylene glycol Structural

What is alpha, oMega-Dipropionic acid hexaethylene glycol?

Description

Bis-PEG7-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Biological Activity

Bis-PEG7-acid is a PROTAC linker belonging to the PEG class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).

Properties of alpha, oMega-Dipropionic acid hexaethylene glycol

form  Viscous Liquid
color  Colorless to light yellow

Safety information for alpha, oMega-Dipropionic acid hexaethylene glycol

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for alpha, oMega-Dipropionic acid hexaethylene glycol

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