ALPHA-BROMOISOBUTYRIC ACID
- CAS NO.:55-52-7
- Empirical Formula: C9H14N2
- Molecular Weight: 150.22
- MDL number: MFCD00865946
- EINECS: 200-236-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is ALPHA-BROMOISOBUTYRIC ACID?
Originator
Catron ,Lakeside, US,1959
Definition
ChEBI: Pheniprazine is a member of amphetamines.
Manufacturing Process
A solution containing 741 g (5.0 mols) of 1 -phenyl-2-propylidenylhydrazine, 300 g (5.0 mols) of glacial acetic acid and 900 cc of absolute ethanol was subjected to hydrogenation at 1,875 psi of hydrogen in the presence of 10 g of platinum oxide catalyst and at a temperature of 30°C to 50°C (variation due to exothermic reaction). The catalyst was removed by filtration and the solvent and acetic acid were distilled. The residue was taken up in water and made strongly alkaline by the addition of solid potassium hydroxide. The alkaline mixture was extracted with ether and the ether extracts dried with potassium carbonate. The product was collected by fractional distillation, BP 85°C (0.30 mm); yield 512 g (68%).
The hydrochloride salt was formed in a mixture of 1:10 isopropyl alcohol:diisopropyl ether and recrystallized from acetonitrile, yield 87%, MP 124°C to 125°C.
brand name
Catron Hydrochloride (Marion Merrell Dow).
Therapeutic Function
Antihypertensive
Safety Profile
Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects by an unspecified route: visual field effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Properties of ALPHA-BROMOISOBUTYRIC ACID
Melting point: | 25°C |
Boiling point: | 261.79°C (rough estimate) |
Density | 0.9372 (rough estimate) |
refractive index | 1.6210 (estimate) |
pka | 8.00±0.70(Predicted) |
Safety information for ALPHA-BROMOISOBUTYRIC ACID
Computed Descriptors for ALPHA-BROMOISOBUTYRIC ACID
Related products of tetrahydrofuran
You may like
-
77-92-9 99%View Details
77-92-9 -
77-92-9 99%View Details
77-92-9 -
8000-27-9 CEDAR WOOD OIL 99%View Details
8000-27-9 -
AMMONIUM DICHROMATE 7789-09-5 99%View Details
7789-09-5 -
7681-57-4 SODIUM METABISULPHITE 99%View Details
7681-57-4 -
77-78-1 DIMETHYL SULPHATE 99%View Details
77-78-1 -
7778-80-5 POTASSIUM SULPHATE 99%View Details
7778-80-5 -
95-54-5 99%View Details
95-54-5