alpha-(4-chlorophenyl)pyridine-2-methanol
- CAS NO.：27652-89-7
- Empirical Formula: C12H10ClNO
- Molecular Weight: 219.67
- MDL number: MFCD00023493
- EINECS: 248-592-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:02:51
What is alpha-(4-chlorophenyl)pyridine-2-methanol?
Chemical properties
Light-Brown Solid
The Uses of alpha-(4-chlorophenyl)pyridine-2-methanol
α-(4-Chlorophenyl)-2-pyridinemethanol is used as a reagent in the synthesis of Carbinoxamine (Maleate salt: C175920), a histamine H1 antagonist. α-(4-Chlorophenyl)-2-pyridinemethanol is also an intermediate in the synthesis of Bepotastine besylate (B317000), a non-sedating H1-antagonist that has anti-inflammatory activity.
Properties of alpha-(4-chlorophenyl)pyridine-2-methanol
| Melting point: | 78-80?C |
| Boiling point: | 364.3±32.0 °C(Predicted) |
| Density | 1.275±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.46±0.20(Predicted) |
| color | Off-White to Grey |
Safety information for alpha-(4-chlorophenyl)pyridine-2-methanol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for alpha-(4-chlorophenyl)pyridine-2-methanol
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product: 4-Chlorophenyl-2-pyridinylmethanol 98%
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