ALLOBARBITAL

CAS NO.：52-43-7
Empirical Formula: C10H12N2O3
Molecular Weight: 208.21
MDL number: MFCD00056090
EINECS: 200-140-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:58

What is ALLOBARBITAL?

Originator

Allobarbital, Fluorochem Ltd.

The Uses of ALLOBARBITAL

Allobarbital is a barbiturate derivative that is primarily used as an anticonvulsant. Allobarbital also shows hypnotic activity and is used to boost the activity of analgesic drugs. Studies show that Allobarbital is an effective promoters of hepatocarcinogenesis. Allobarbital is a Controlled Substance.

Definition

ChEBI: Allobarbital is a member of barbiturates.

Manufacturing Process

To a mixture of 43 parts barbituric acid, 200 parts of water and 5 parts of cuprous sulfate in 10 parts of water is added 82 parts of allylbromide. Then at room temperature is added 27 parts of sodium hydroxide (10% aqueous solution). 5,5-Diallylbarbituric acid is isolated by filtration. After recrystallization from water 5,5-diallylbarbituric acid has melting polint 169- 170°C.

Therapeutic Function

Sedative, Hypnotic

Properties of ALLOBARBITAL

Melting point:	171-173°
Boiling point:	347.41°C (rough estimate)
Density	1.2420 (rough estimate)
refractive index	1.4830 (estimate)
storage temp.	2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	7.67±0.10(Predicted)
form	Solid
color	White to Orange
Water Solubility	1.77g/L(25 ºC)
EPA Substance Registry System	2,4,6(1H,3H,5H)-Pyrimidinetrione, 5,5-di-2-propen-1-yl- (52-43-7)