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HomeProduct name listAlgestone acetophenide

Algestone acetophenide

  • CAS NO.:24356-94-3
  • Empirical Formula: C29H36O4
  • Molecular Weight: 448.6
  • MDL number: MFCD00056835
  • EINECS: 246-195-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
Algestone acetophenide Structural

What is Algestone acetophenide?

Originator

Neolutin Depo, Medici ,Italy ,1982

The Uses of Algestone acetophenide

Algestone Acetophenide is a progestational steroid that has been shown to increase the proteins in milk and serum in goats and decrease the weight gain of kids. Algestone Acetophenide is used as an injectable steroid contraceptive in Chile and Mexico.

The Uses of Algestone acetophenide

Progestin.

Definition

ChEBI: Algestone acetophenide is a 16alpha,17alpha-dihydroxyprogesterone acetophenide. It has a role as an anti-inflammatory drug and a synthetic oral contraceptive.

Manufacturing Process

To a suspension of 500 mg of 16α,17α-dihydroxyprogesterone in 25 ml of freshly redistilled acetophenone is added 0.125 ml of 72% perchloric acid and the mixture is agitated at room temperature for one hour. The clear solution is washed with dilute sodium bicarbonate to remove excess acid and the acetophenone layer, after addition of chloroform is separated from the aqueous phase. The organic layer is dried over sodium sulfate and after removal of the chloroform and acetophenone in high vacuum the residue is crystallized from 95% alcohol. The pure acetophenone derivative has a melting point of about 142°C to 144°C.

brand name

Deladroxone (Bristol-Myers Squibb); Droxone (Bristol-Myers Squibb).

Therapeutic Function

Progestin, Contraceptive

Properties of Algestone acetophenide

Melting point: 150-151°
Boiling point: 477.29°C (rough estimate)
alpha  D23 +51° (CHCl3)
Density  1.0455 (rough estimate)
refractive index  1.4800 (estimate)
storage temp.  Refrigerator
solubility  Chloroform (Sparingly), Methanol (Slightly)
form  Solid
color  White to Off-White
CAS DataBase Reference 24356-94-3(CAS DataBase Reference)

Safety information for Algestone acetophenide

Computed Descriptors for Algestone acetophenide

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