AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
- CAS NO.：54472-66-1
- Empirical Formula: C78H108N18O21S2
- Molecular Weight: 1697.95
- MDL number: MFCD08459563
- Update Date: 2023-05-21 10:59:17
What is AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT?
Description
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors). It inhibits cAMP accumulation induced by forskolin in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively). Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.
Properties of AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
| storage temp. | Store at -20°C |
| solubility | Water: 0.3 mg/ml |
| form | A powder |
Safety information for AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
Computed Descriptors for AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
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