AF12198
- CAS NO.:185413-30-3
- Empirical Formula: C96H123N19O22
- Molecular Weight: 1895.12
- MDL number: MFCD02259571
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is AF12198?
The Uses of AF12198
AF 12198 is a peptide that selectively binds Interleukin-1 (IL-1) receptor and blocks in vivo responses to IL-1 (1). The interleukin-1 receptor can activate the innate immune response by binding to cytokines (2). Dysregulation of cytokine production can lead to aberrant immune cells activation that could result in auto-inflammatory disorders.
storage
Store at -20°C
Properties of AF12198
Melting point: | >179°C (dec.) |
Density | 1.353±0.06 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | DMSO (Slightly), Methanol (Slightly), Water (Very Slightly) |
form | solid |
pka | 4.44±0.10(Predicted) |
color | White to Off-White |
Safety information for AF12198
Computed Descriptors for AF12198
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Rimegepant Impurity 3 Ivermectin EP Impurity B Tubulysin G Tubulysin F (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin B 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Fuel shell Calcium Sodium Phosphosilicate IH Imeglimin Hydrochloride IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-Chloro-3-(chloromethyl)pyridine Methyl 4-amino-3-(piperidin-1-yl)benzoate 5-Aminophthalazine (1-Isopropyl-1H-pyrazol-5-yl)boronic acid Methyl 4-amino-3-(pyrrolidin-1-yl)benzoate 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 4-BROMO-5-FLUORONAPHTHALEN-2-OL 3,3-dimethyl-2-oxo-, methyl ester 3,6-DICHLORO -4-ISOPROPYLPYRIDAZINERelated products of tetrahydrofuran
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