AF12198
- CAS NO.：185413-30-3
- Empirical Formula: C96H123N19O22
- Molecular Weight: 1895.12
- MDL number: MFCD02259571
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is AF12198?
The Uses of AF12198
AF 12198 is a peptide that selectively binds Interleukin-1 (IL-1) receptor and blocks in vivo responses to IL-1 (1). The interleukin-1 receptor can activate the innate immune response by binding to cytokines (2). Dysregulation of cytokine production can lead to aberrant immune cells activation that could result in auto-inflammatory disorders.
storage
Store at -20°C
Properties of AF12198
| Melting point: | >179°C (dec.) |
| Density | 1.353±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Very Slightly) |
| form | solid |
| pka | 4.44±0.10(Predicted) |
| color | White to Off-White |
Safety information for AF12198
Computed Descriptors for AF12198
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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