ADIPAMIDE

Description

Adipamide is a chunky white powder. It is slightly soluble in water and incompatible with strong oxidising agents. Adipamide on combustion and decomposition produces hazardous products of toxic fumes of carbon monoxide, carbon dioxide, and nitrogen oxides. Exposures to adipamide by inhalation, ingestion, or skin absorption cause adverse health. The symptoms include irritation of the eyes, skin, mucous membranes, and upper respiratory tract. There is no complete information about the toxicological properties of the chemical.

Chemical properties

Adipamide is white powder and chunks. It is slightly soluble in water and incompatible with strong oxidizing agents. On combustion and decomposition, adipamide produces toxic fumes of carbon monoxide, carbon dioxide, and nitrogen oxides.

Chemical properties

Adipamide is powder in appearance and slightly soluble in water. It is incompatible with strong oxidizing agents. On combustion or decomposition, adipamide releases hazardous products, toxic fumes of carbon monoxide, carbon dioxide, and nitrogen oxides.

The Uses of ADIPAMIDE

Adipamide has been used in the preparation of bisimidates.

Definition

ChEBI: Adipamide is a fatty amide.

Preparation

Adipamide has been traditionally prepared from the dimethyl ester by treatment with concentrated ammonium hydroxide or by heating the diammonium salt of adipic acid in a stream of ammonia. Other substituted amides can be prepared from amines by the usual synthetic methods.

General Description

Colorless powder.

Air & Water Reactions

Slightly soluble in water .

Reactivity Profile

ADIPAMIDE forms flammable gases with strong reducing agents. A very weak base. Mixing with dehydrating agents such as P2O5 or SOCl2 generates adiponitrile. Combustion generates toxic mixed oxides of nitrogen (NOx).

Health Hazard

Exposures to adipamide by inhalation, ingestion, or skin absorption cause adverse health effects. The symptoms include irritation of the eyes, skin, mucous membranes, and upper respiratory tract. There is no complete information about the toxicological properties of the chemical.

Health Hazard

Exposures to adipamide cause health disorders such as irritation to the skin, eyes, and respiratory system. No specifi c adverse health effects have been reported from human exposure to polyhexamethylene adipamide, except for mechanical irritation of the skin and eyes caused by particles. Signifi cant skin permeation and systemic toxicity after contact appears unlikely. The compound is not likely to be hazardous by skin contact, but cleansing the skin after use is advisable. If molten polymer gets on the skin, cool rapidly with cold water. Workers should not attempt to peel polymer from skin, but consult a medical unit for treatment of thermal burn.

Fire Hazard

The flash point of ADIPAMIDE has not been determined, but ADIPAMIDE is probably combustible.

Safety Profile

Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of NOx,.

storage

Adipamide should be kept stored in a cool, dry place, with containers tightly closed to prevent moisture absorption and contamination.

storage

Workers should avoid repeated exposures to adipamide. During use, workers should wear suitable protective clothing, self-contained breathing apparatus, chemical safety goggles, rubber boots, and heavy rubber gloves.

Precautions

During use and handling of adipamide, workers should wear self-contained breathing apparatus, rubber boots, heavy rubber gloves, and chemical safety goggles to avoid splashing of material. A full-face mask respirator provides protection from eye irritation. Workers should avoid exposure to high concentrations of dust. No specifi c intervention is indicated as the compound is not likely to be hazardous by inhalation. Consult a physician if necessary. If exposed to fumes from overheating or combustion, move to fresh air. Consult a physician if symptoms persist.