Acetylene-PEG4-biotin conjugate

Synonym(s):Acetylene-PEG4-biotin conjugate

CAS NO.：1458576-00-5
Empirical Formula: C21H35N3O6S
Molecular Weight: 457.58
MDL number: MFCD22380755
Update Date: 2024-11-05 08:26:49

Acetylene-PEG4-biotin conjugate Structural

What is Acetylene-PEG4-biotin conjugate?

Description

Biotin-PEG4-alkyne is click chemistry biotinylation reagent. The alkyne group is reactive with azide moiety via Click Chemistry reaction to form a stable triazole linkage. PEG arm increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

The Uses of Acetylene-PEG4-biotin conjugate

An acetylene-biotin conjugate with PEG spacer

Properties of Acetylene-PEG4-biotin conjugate

Melting point:	55-64 °C
Boiling point:	707.1±60.0 °C(Predicted)
Density	1.158±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in Water, DMSO, DCM, DMF
pka	13.90±0.40(Predicted)
form	Solid
color	White to light yellow

Safety information for Acetylene-PEG4-biotin conjugate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P403+P233:Store in a well-ventilated place. Keep container tightly closed.