Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listAbunidazole

Abunidazole

Abunidazole Structural

What is Abunidazole?

Originator

Abunidazole,ZYF Pharm Chemical

Manufacturing Process

150.0 g (1 mol) of p-tert-butylphenol are dissolved in 1200 ml of anhydrous ethyl ether and the thus obtained solution is added to a 10% solution of ethylmagnesium bromide in 1000 ml of anhydrous ether, at room temperature, under stirring.
After having evaporated the ether, 1000 ml of anhydrous benzene are added and the mixture is distilled, at normal pressure, until its volume is about 2/3 of the original volume. After cooling at room temperature, 1 mol of 1-methyl- 5-nitroimidazolyl-2-carboxyaldehyde in 1000 ml of anhydrous benzene is added.
The whole is boiled for 1 h, is cooled to about 10°C and is added with 8% HCl to adjust the pH to 7. Benzene layer is dried and concentrated up to 2/3 of the volume. The 2-(1-methyl-5-nitro)imidazolyl-1-(2-hydroxy-5-tertbutylphenylcarbinol is allowed to crystallize, melting point 158°-160°C; yield 0-60%.

Therapeutic Function

Antiprotozoal

Properties of Abunidazole

Boiling point: 529.4±50.0 °C(Predicted)
Density  1.30±0.1 g/cm3(Predicted)
pka 9.57±0.48(Predicted)

Safety information for Abunidazole

Computed Descriptors for Abunidazole

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.