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HomeProduct name listA 71623

A 71623

A 71623 Structural

What is A 71623?

The Uses of A 71623

A-71623 is a potent CCK agonist with 1200-fold selectivity over the CCK2 receptor.

What are the applications of Application

A-71623 is a potent CCK agonist with 1200-fold selectivity over the CCK2 receptor

Biological Activity

Potent CCK 1 agonist (IC 50 = 3.7 nM) with 1200-fold selectivity over the CCK 2 receptor. Suppresses food intake following central or peripheral administration.

storage

Store at -20°C

References

[1]. gracey dj, bell r, king dj. differential effects of the ccka receptor ligands pd-140,548 and a-71623 on latent inhibition in the rat. progress in neuro-psychopharmacology and biological psychiatry, 2002, 26(3): 497-504.
[2]. lin cw, shiosaki k, miller tr, et al. characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, a-71623 and a-70874, that exhibit high potency and selectivity for cholecystokinin-a receptors. molecular pharmacology, 1991, 39(3): 346-351.
[3]. kaufmann r, lindschau c, scho t, et al. type b cholecystokinin receptors on rat glioma c6 cells. binding studies and measurement of intracellular calcium mobilization. brain research, 1994, 639(1): 109-114.

Properties of A 71623

storage temp.  Desiccate at -20°C
solubility  Soluble to 1 mg/ml in 20mM PBS buffer
form  solid
color  White

Safety information for A 71623

Computed Descriptors for A 71623

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