9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID

CAS NO.：17968-82-0
Empirical Formula: C20H34O5
Molecular Weight: 354.48
MDL number: MFCD00216039
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

What is 9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID?

Description

Prostaglandin D₁ (PGD₁) is the 1-series analog of PGD₂ . It is an inhibitor of ADP-induced platelet aggregation in humans with an IC₅₀ value of 320 ng/ml, about 1/10 as potent as PGD₂.

The Uses of 9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID

Prostaglandin D1 is used in pharmalogical and in functional characterization of novel EP & DP receptor agonist: DPI receptor mediates penile erection in multiple species.

What are the applications of Application

Prostaglandin D1 is a relatively weak inhibitor of ADP-induced platelet aggregation

Definition

ChEBI: Prostaglandin D1 is a prostaglandins D. It has a role as a human metabolite. It is a conjugate acid of a prostaglandin D1(1-).

Properties of 9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID

Melting point:	64.5-65.5 °C
Boiling point:	544.6±50.0 °C(Predicted)
Density	1.131±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >5 mg/ml (from PGD2)
pka	4.78±0.10(Predicted)