9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID
- CAS NO.：69413-73-6
- Empirical Formula: C20H32O5
- Molecular Weight: 352.47
- MDL number: MFCD00216081
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:03:09
What is 9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID?
Description
Prostaglandin K1 (PGK1) is a 9,11-diketo analog of PGE1 or PGD1 . It is a PGE2 receptor subtype EP1 agonist that has 387-fold reduced potency compared to PGE2 .1
What are the applications of Application
Prostaglandin K1 is the 9,11-diketone formed by the oxidation of PGE1 or PGD1
Definition
ChEBI: PGK1 is a prostanoid.
References
1. Ungrin, M.D., Carrière, M.C., Denis, D., et al. Key structural features of prostaglandin E2 and prostanoid analogs involved in binding and activation of the human EP1 prostanoid receptor Mol. Pharmacol. 59(6),1446-1456(2001).
Properties of 9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID
| Boiling point: | 551.8±50.0 °C(Predicted) |
| Density | 1.127±0.06 g/cm3(Predicted) |
| solubility | DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-d12, |
| pka | 4.77±0.10(Predicted) |
Safety information for 9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID
Computed Descriptors for 9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID
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