9-AMINOACRIDINE
Synonym(s):9-Acridinylamine, Aminacrine;9-Aminoacridine;Aminacrine
- CAS NO.:90-45-9
- Empirical Formula: C13H10N2
- Molecular Weight: 194.23
- MDL number: MFCD00037839
- EINECS: 201-995-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-12 17:13:25
What is 9-AMINOACRIDINE?
Chemical properties
yellow crystals or powder
The Uses of 9-AMINOACRIDINE
Acridine analog. DNA intercalating agent.
The Uses of 9-AMINOACRIDINE
antibacterial
The Uses of 9-AMINOACRIDINE
A MALDI matrix exhibiting low background and good sensitivity in the analysis of low molecular weight anions, such as metabolites, in negative mode
What are the applications of Application
9-Aminoacridine free base is a mutagenic fluorescent dye and an intracellular pH indicator
Definition
ChEBI: An aminoacridine that is acridine in which the hydrogen at position 9 is replaced by an amino group. A fluorescent dyd and topical antiseptic agent, it is used (usually as the hydrochloride salt) in eye drops for the treatment of superficial eye infections
brand name
Monacrin (Sterling Winthrop).
General Description
Yellow needles. Free soluble in alcohol.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
9-AMINOACRIDINE is a moderately strong base. Neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.
Fire Hazard
Flash point data for 9-AMINOACRIDINE are not available; however, 9-AMINOACRIDINE is probably combustible.
Purification Methods
It crystallises from EtOH or acetone and sublimes at 170-180o/0.04mm [Albert & Ritchie Org Synth Coll Vol III 53 1955, for hydrochloride, see below]. [Beilstein 22 H 463, 21 II 280, 21 III/IV 4174.]
Properties of 9-AMINOACRIDINE
Melting point: | 238-240℃ |
Boiling point: | 320.68°C (rough estimate) |
Density | 1.268 |
refractive index | 1.5014 (estimate) |
storage temp. | Store below +30°C. |
solubility | ethanol: hazy |
form | Solid |
pka | 9.99(at 20℃) |
color | Yellow |
Water Solubility | 11.65mg/L(24 ºC) |
λmax | 406nm(DMF)(lit.) |
Merck | 14,407 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 90-45-9(CAS DataBase Reference) |
EPA Substance Registry System | 9-Aminoacridine (90-45-9) |
Safety information for 9-AMINOACRIDINE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 Environment GHS09 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H410:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 9-AMINOACRIDINE
InChIKey | XJGFWWJLMVZSIG-UHFFFAOYSA-N |
New Products
(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION XANTHAN GUM Racecadotril SODIUM VALPROATE Diclofenac Sodium Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN Folic Acid Impurity G Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt Glycopyrronium Bromide EP Impurity I Eltrombopag N-Oxide Impurity Di-Nitroso Acyclovir Impurity K DLRD N-OxideRelated products of tetrahydrofuran
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