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Home Product name list8-ISO PROSTAGLANDIN F2BETA

8-ISO PROSTAGLANDIN F2BETA

CAS NO.：177020-26-7
Empirical Formula: C20H34O5
Molecular Weight: 354.48
MDL number: MFCD00216066
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 20:33:22

8-ISO PROSTAGLANDIN F2BETA Structural

What is 8-ISO PROSTAGLANDIN F2BETA?

Description

8-iso Prostaglandin F_2β (8-iso PGF_2β) is an isomer of PGF_2α with a non-enzymatic, non-cyclooxygenase origin. It is one of 64 possible isomers of PGF_2α which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF_2β exhibits very weak contraction of human umbilical vein artery and does not promote aggregation of human whole blood. However, 8-iso PGF_2β moderately contracts both the canine and porcine pulmonary vein, although the effect is much weaker than that exhibited by other isoprostanes such as 8-iso PGE₁, 8-iso PGE₂, or 8-iso PGF_2α

What are the applications of Application

8-iso Prostaglandin F2β is a prostaglandin able to induce weak vascular contractions

Properties of 8-ISO PROSTAGLANDIN F2BETA

Boiling point:	531.0±50.0 °C(Predicted)
Density	1.153±0.06 g/cm3(Predicted)
solubility	10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
pka	4.76±0.10(Predicted)

Safety information for 8-ISO PROSTAGLANDIN F2BETA

Computed Descriptors for 8-ISO PROSTAGLANDIN F2BETA

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8-ISO PROSTAGLANDIN F2BETA

8-ISO PROSTAGLANDIN F2BETA

9ALPHA,11ALPHA,15S-TRIHYDROXY-(8BETA)-PROSTA-5Z,13E-DIEN-1-OIC-9-3H ACID

9ALPHA,11ALPHA,15S-TRIHYDROXY-(8BETA)-PROSTA-5Z,13E-DIEN-1-OIC-9-3H ACID

8-EPI PROSTAGLANDIN F2ALPHA-D4

8-EPI PROSTAGLANDIN F2ALPHA-D4

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