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HomeProduct name list8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER

8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER

8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER Structural

What is 8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER?

Description

8-iso PGE2 isopropyl ester is a more lipophilic form of the free acid, 8-iso PGE2. Prostaglandin esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of prostaglandins show greatly diminished agonist activity in vitro compared to the parent free acids.

What are the applications of Application

8-iso Prostaglandin E2 isopropyl ester is which has shown both vasoconstriction and vasodilation activity

Properties of 8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER

Boiling point: 511.8±50.0 °C(Predicted)
Density  1.079±0.06 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  DMF: >30 mg/ml (from PGF2a isopropy; DMSO: >50 mg/ml (from PGF2a isopropy; Ethanol: >50 mg/ml (from PGF2a isopropy; PBS pH 7.2: <50 μg/ml (from PGF2a isopropy
pka 13.79±0.60(Predicted)

Safety information for 8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER

Computed Descriptors for 8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER

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