8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
- CAS NO.：666816-98-4
- Empirical Formula: C10H9BrN4O2
- Molecular Weight: 297.11
- MDL number: MFCD22126091
- EINECS: 613-975-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-13 21:11:14
What is 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione?
Chemical properties
White powder
Synthesis
8-bromo-3-methyl-3,7-dihydro-1H-purine-2,6-dione (2.450 g, 10 mmol),1-bromo-2-butyne (1.596 g, 12 mmol), Sodium carbonate (1.590 g, 15 mmol), and 20mL of acetone was added to a 100mL flask. The reaction system was heated to 40 ° C, and the reaction was stirred for 4h. After the reaction was cooled to room temperature, suction filtration was performed, and the filter cake was washed with methanol to obtain a crude product as a pale yellow solid. The crude product was reconstituted with dichloromethane and cyclohexane. Yield 2.912 g of 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione. The yield was 98%, and the purity was 99.9%.
Properties of 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
| Melting point: | 285 °C |
| Density | 1.71 |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 8.91±0.70(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| CAS DataBase Reference | 666816-98-4 |
Safety information for 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
Computed Descriptors for 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione manufacturer
Mekanar Pharma Private Limited
1Y
Phone:+919948050784
Whatsapp: +91- 9948050784
product: 666816-98-4 99%
ELIXIR PHARMA
Beijing
Phone:91-9558826007
Whatsapp: 91-9558826007
product: 8-Bromo-3-methyl-7-but-2-ynyl xanthine
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