8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER
- CAS NO.:250685-44-0
- Empirical Formula: C27H29N3O3
- Molecular Weight: 443.54
- MDL number: MFCD04113779
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:16
What is 8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER?
The Uses of 8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER
8-(1-Naphthalenylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-3-acetic acid Methyl Ester is a potent nociceptin receptor agonist.
What are the applications of Application
NNC 63-0532 is a potent non-peptide agonist for the NOP receptor
Biological Activity
Potent non-peptide agonist for the NOP receptor (EC 50 = 305 nM, K i = 7.3 nM); ~ 12-fold selective over other receptors. Centrally active following systemic administration in vivo .
storage
Store at RT
Properties of 8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER
storage temp. | Store at RT |
solubility | Soluble to 5 mM in ethanol and to 50 mM in DMSO |
form | Powder |
color | White to off-white |
Safety information for 8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER
Computed Descriptors for 8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER
New Products
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8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER
8-benzyl-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one
PIPERIDINE-4-CARBOXYLIC ACID (2-METHOXY-ETHYL)-AMIDE
N-BENZYL-4-AMINO-PIPERIDINE-4-CARBOXAMIDE
1-(1-BENZYLPIPERIDIN-4-YL)-N-METHYLMETHANAMINE
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