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HomeProduct name list7,8-DIHYDROXY-6-METHOXYCOUMARIN

7,8-DIHYDROXY-6-METHOXYCOUMARIN

Synonym(s):7,8-Dihydroxy-6-methoxycoumarin;Fraxetin

  • CAS NO.:574-84-5
  • Empirical Formula: C10H8O5
  • Molecular Weight: 208.17
  • MDL number: MFCD00006873
  • EINECS: 209-376-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
7,8-DIHYDROXY-6-METHOXYCOUMARIN Structural

What is 7,8-DIHYDROXY-6-METHOXYCOUMARIN?

The Uses of 7,8-DIHYDROXY-6-METHOXYCOUMARIN

Fraxetin is a coumarin compound with anti-oxidant and anti-inflammatory activity. Also acts as a protective agent against hyperuricemia and renal dysfunction.

Definition

ChEBI: Fraxetin is a hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups. It has a role as an Arabidopsis thaliana metabolite, an antimicrobial agent, an apoptosis inhibitor, an apoptosis inducer, an antioxidant, an anti-inflammatory agent, a hepatoprotective agent, an antibacterial agent and a hypoglycemic agent. It is a hydroxycoumarin and an aromatic ether.

Properties of 7,8-DIHYDROXY-6-METHOXYCOUMARIN

Melting point: 230-231 °C (lit.)
Boiling point: 307.35°C (rough estimate)
Density  1.3844 (rough estimate)
refractive index  1.4717 (estimate)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  DMSO : 250 mg/mL (1200.94 mM; Need ultrasonic)
form  neat
pka 7.22±0.20(Predicted)
form  Solid
color  White
Merck  13,4288
Stability: Hygroscopic
CAS DataBase Reference 574-84-5(CAS DataBase Reference)

Safety information for 7,8-DIHYDROXY-6-METHOXYCOUMARIN

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501:Dispose of contents/container to..…

Computed Descriptors for 7,8-DIHYDROXY-6-METHOXYCOUMARIN

InChIKey HAVWRBANWNTOJX-UHFFFAOYSA-N

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