7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT
Synonym(s):m7GTP
- CAS NO.：104809-18-9
- Empirical Formula: C11H18N4NaO14P3
- Molecular Weight: 546.19
- MDL number: MFCD00063376
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 15:09:34
What is 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT?
The Uses of 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT
7-Methylguanosine 5′-triphosphate (m7GTP) is use to study the structures and mechanisms of eukaryotic cellular mRNA caps in the context of mRNA involvement in protein synthesis. m7GTP may be used to create affinity media for capture and purification of molecules such as eukaryotic initiation factor eIF4E.
General Description
7-Methylguanosine 5′-triphosphate is a mRNA cap structural analog.
Biochem/physiol Actions
7-Methylguanosine 5′-triphosphate (m7GTP) inhibits in vitro protein synthesis by binding to translation initiation complexes. m7GTP is useful to study the structures and mechanisms of eukaryotic cellular mRNA caps in the context of mRNA involvement in protein synthesis. m7GTP has a high affinity for eukaryotic initiation factor eIF4E and may be used to create affinity media for their capture and purification.
Properties of 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT
| storage temp. | -20°C |
Safety information for 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT
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