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HomeProduct name list6-tert-Butyl-2,3-naphthalenedicarbonitrile

6-tert-Butyl-2,3-naphthalenedicarbonitrile

Synonym(s):BRD9876

6-tert-Butyl-2,3-naphthalenedicarbonitrile Structural

What is 6-tert-Butyl-2,3-naphthalenedicarbonitrile?

The Uses of 6-tert-Butyl-2,3-naphthalenedicarbonitrile

6-tert-Butyl-2,3-naphthalenedicarbonitrile is a stain with bioloigcal research applications. Dyes and metabolites.

What are the applications of Application

6-tert-Butyl-2,3-naphthalenedicarbonitrile is a stain with bioloigcal research applications

Definition

ChEBI: 6-tert-butylnaphthalene-2,3-dicarbonitrile is a member of naphthalenes.

Biological Activity

BRD9876 is an inhibitor of the kinesin spindle protein Eg5. It arrests Eg5-mediated microtubule gliding, as well as inhibits Eg5 ATPase activity in the presence of microtubules, in cell-free assays. BRD9876 is cytotoxic to MM.1S stroma-independent multiple myeloma cells (IC50 = 2.2 μM). It induces cell cycle arrest at the G2/M phase in MM.1S cells when used at a concentration of 10 μM.

Properties of 6-tert-Butyl-2,3-naphthalenedicarbonitrile

Melting point: 185-189 °C(lit.)
Boiling point: 429.7±33.0 °C(Predicted)
Density  1.11±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
form  Solid
color  Pale Yellow to Light Beige

Safety information for 6-tert-Butyl-2,3-naphthalenedicarbonitrile

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Computed Descriptors for 6-tert-Butyl-2,3-naphthalenedicarbonitrile

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