6-tert-Butyl-2,3-naphthalenedicarbonitrile
Synonym(s):BRD9876
- CAS NO.：32703-82-5
- Empirical Formula: C16H14N2
- Molecular Weight: 234.3
- MDL number: MFCD00209558
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-31 18:15:48
What is 6-tert-Butyl-2,3-naphthalenedicarbonitrile?
The Uses of 6-tert-Butyl-2,3-naphthalenedicarbonitrile
6-tert-Butyl-2,3-naphthalenedicarbonitrile is a stain with bioloigcal research applications. Dyes and metabolites.
What are the applications of Application
6-tert-Butyl-2,3-naphthalenedicarbonitrile is a stain with bioloigcal research applications
Definition
ChEBI: 6-tert-butylnaphthalene-2,3-dicarbonitrile is a member of naphthalenes.
Biological Activity
BRD9876 is an inhibitor of the kinesin spindle protein Eg5. It arrests Eg5-mediated microtubule gliding, as well as inhibits Eg5 ATPase activity in the presence of microtubules, in cell-free assays. BRD9876 is cytotoxic to MM.1S stroma-independent multiple myeloma cells (IC50 = 2.2 μM). It induces cell cycle arrest at the G2/M phase in MM.1S cells when used at a concentration of 10 μM.
Properties of 6-tert-Butyl-2,3-naphthalenedicarbonitrile
| Melting point: | 185-189 °C(lit.) |
| Boiling point: | 429.7±33.0 °C(Predicted) |
| Density | 1.11±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly) |
| form | Solid |
| color | Pale Yellow to Light Beige |
Safety information for 6-tert-Butyl-2,3-naphthalenedicarbonitrile
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
Computed Descriptors for 6-tert-Butyl-2,3-naphthalenedicarbonitrile
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