6-METHYLAMINOPURINE 9-RIBOFURANOSIDE
- CAS NO.：1867-73-8
- Empirical Formula: C11H15N5O4
- Molecular Weight: 281.27
- MDL number: MFCD00005739
- EINECS: 200-001-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-19 17:28:17
What is 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE?
Description
N6-Methyladenosine is an adenosine analog. It inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta when used at a concentration of 10 μM. N6-Methyladenosine (1 mg/kg, i.v.) decreases arterial blood pressure and renal blood flow and increases peripheral resistance in anesthetized dogs. It also inhibits tumor growth in the C3H/ST and C3HB/ST mouse models of spontaneous mammary adenocarcinomas. N6-Methyladenosine is also the most prevelant mRNA modification in eukaryotes and has roles in cell viability and development.
The Uses of 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE
N6-Methyladenosine is the most common internal modification of eukaryotic mRNA. The result of this modification is specifically recognized mRNA in the cytoplasm which regulates mRNA stability.N6-Methyladenosine is made when a protein complex containin the writer enzyme METTL3 adds a methyl group to adenosine. Two different eraser enzymes ALKBH5 and FTO can remove a methyl group to turn m6A bach into adenosine.
Definition
ChEBI: A methyladenosine compound with one methyl group attached to N6 of the adenine nucleobase.
Properties of 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE
| Melting point: | 172 °C |
| Boiling point: | 649.1±65.0 °C(Predicted) |
| Density | 1.85±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| form | Powder |
| pka | 13.12±0.70(Predicted) |
| color | White to off-white |
| Stability: | Hygroscopic |
Safety information for 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE
Computed Descriptors for 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Boc-His(Boc)-OH 2-CTC Resin 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 5,7-Dibromo-1H-indole 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID 4-((2-hydroxyethyl)thio)benzoic acid 1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE Methyl 6-methylnicotinate 3-Pyridineacrylic acid tert-Butyl carbazate TETRAHYDRO-2H-PYRAN-3-OL 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 2,4-dihydroxybenzaldehyde 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylateRelated products of tetrahydrofuran
![[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-oxolan-2-yl]methoxyphosphonic acid](https://img.chemicalbook.in/CAS/GIF/1053-73-2.gif)
![[(2R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-oxolan-2-yl]me thoxyphosphonic acid](https://img.chemicalbook.in/CAS/GIF/3805-37-6.gif)
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