6-HYDROXYFLAVANONE
- CAS NO.：4250-77-5
- Empirical Formula: C15H12O3
- Molecular Weight: 240.25
- MDL number: MFCD00017485
- EINECS: 624-472-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is 6-HYDROXYFLAVANONE?
Chemical properties
Slightly yellow-cream powder
The Uses of 6-HYDROXYFLAVANONE
6-Hydroxyflavanone (6-HF) has been used for the enantiomeric separation of flavonoids using polysaccharide-based chiral stationary phases by nano-liquid chromatography (nano-LC). Racemic 6-HF may be used in the synthesis of 6-propionoxy-flavanone (6-PF). 6-HF may be employed as synthetic flavone to investigate the mechanism of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced cytotoxic and apoptotic effects in HeLa cancer cells.
What are the applications of Application
6-Hydroxyflavanone is a useful biochemical flavonoid for proteomics research
Definition
ChEBI: A monohydroxyflavanone that is flavanone substituted by a hydroxy group at position 6.
General Description
6-Hydroxyflavanone is a flavonoid. Its biotransformation by Aspergillus niger strains have been described. Crystal structure of S and R enanti-omers of 6-hydroxyflavanone has been reported to have four crystallographic sites of the unit cell in an approximate 3:1/1:3 ratio. It was identified as a metabolite of flavnone on incubation with rat liver microsomes by positive ion electrospray LC/MS analysis.
Properties of 6-HYDROXYFLAVANONE
| Melting point: | 220-222 °C (dec.) (lit.) |
| Boiling point: | 464.3±45.0 °C(Predicted) |
| Density | 1.288±0.06 g/cm3(Predicted) |
| form | powder to crystal |
| pka | 9.53±0.40(Predicted) |
| color | White to Orange to Green |
| BRN | 87354 |
| CAS DataBase Reference | 4250-77-5(CAS DataBase Reference) |
Safety information for 6-HYDROXYFLAVANONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 6-HYDROXYFLAVANONE
6-HYDROXYFLAVANONE manufacturer
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