6-Chloro-2,3-diaminotoluene

CAS NO.：673487-36-0
Empirical Formula: C7H9ClN2
Molecular Weight: 156.61
MDL number: MFCD09026957
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-26 15:31:11

What is 6-Chloro-2,3-diaminotoluene?

The Uses of 6-Chloro-2,3-diaminotoluene

6-Chloro-2,3-diaminotoluene is a white solid powder at room temperature and pressure, with significant alkalinity and strong nucleophilicity. Due to the presence of two amino units in the ortho position of the benzene ring, it can undergo condensation reactions with aldehydes to prepare corresponding benzimidazole derivatives. This reaction is widely used to prepare benzimidazole drugs and bioactive molecules. It is an intermediate in organic synthesis and medicinal chemistry, such as Nemonapride.

Properties of 6-Chloro-2,3-diaminotoluene

Melting point:	46-47 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
Boiling point:	305.6±37.0 °C(Predicted)
Density	1.281±0.06 g/cm3(Predicted)
pka	3.65±0.10(Predicted)

Safety information for 6-Chloro-2,3-diaminotoluene

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.