6-Bromo-1-hexanol

Synonym(s):Hexamethylene bromohydrin

CAS NO.：4286-55-9
Empirical Formula: C6H13BrO
Molecular Weight: 181.07
MDL number: MFCD00002983
EINECS: 610-072-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-24 21:11:45

What is 6-Bromo-1-hexanol?

Chemical properties

colourless or light yellow liquid

The Uses of 6-Bromo-1-hexanol

6-Bromo-1-hexanol is a useful synthetic intermediate. 6-Bromo-1-hexanol is used as a reagent in the preparation of nitric oxide-donating analogues of Sulindac (S699215), a non-steroidal anti-inflammatory drug that has the ability to prevent colon cancer.

The Uses of 6-Bromo-1-hexanol

A product for proteomics research. Also used as a reagent in the preparation of nitric oxide-donating analogues of Sulindac (S699215), a non-steroidal anti-inflammatory drug that has the ability to prevent colon cancer.

What are the applications of Application

6-Bromo-1-hexanol is a product for proteomics research

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 5137, 1950 DOI: 10.1021/ja01167a091
Synthesis, p. 1161, 1985 DOI: 10.1055/s-1985-31464
Tetrahedron Letters, 36, p. 711, 1995 DOI: 10.1016/0040-4039(94)02340-H

Properties of 6-Bromo-1-hexanol

Boiling point:	105-106 °C5 mm Hg(lit.)
Density	1.384 g/mL at 25 °C(lit.)
vapor pressure	0.25Pa at 20℃
refractive index	n20/D 1.482(lit.)
Flash point:	>230 °F
storage temp.	2-8°C
solubility	Soluble in chloroform and methanol.
form	Oil
pka	15.16±0.10(Predicted)
color	Clear Colorless
BRN	1732415
Stability:	Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides.
CAS DataBase Reference	4286-55-9(CAS DataBase Reference)
EPA Substance Registry System	1-Hexanol, 6-bromo- (4286-55-9)

Safety information for 6-Bromo-1-hexanol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.