6-aminocarbovir
Synonym(s):(1S,4R)-4-[2,6-Diamino-9H-purin-9-yl]-2-cyclopentene-1-methanol
- CAS NO.：124752-25-6
- Empirical Formula: C11H14N6O
- Molecular Weight: 246.27
- MDL number: MFCD00869644
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 6-aminocarbovir?
Chemical properties
Off-White to Pale Yellow Solid
The Uses of 6-aminocarbovir
Abacavir Intermediate.
The Uses of 6-aminocarbovir
Descyclopropyl Abacavir (Abacavir EP Impurity C; Abacavir Related Compound A) is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Properties of 6-aminocarbovir
| Melting point: | 180-182°C |
| Boiling point: | 628.2±65.0 °C(Predicted) |
| Density | 1.75±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | neat |
| pka | 14.86±0.10(Predicted) |
| color | Off-White to Pale Yellow |
Safety information for 6-aminocarbovir
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 6-aminocarbovir
Abamectin manufacturer
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product: Abacavir amine impurity 98%
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