6-Amino-m-cresol
Synonym(s):2-Hydroxy-4-methylaniline;4-Amino-3-hydroxytoluene;6-Amino-m-cresol
- CAS NO.：2835-98-5
- Empirical Formula: C7H9NO
- Molecular Weight: 123.15
- MDL number: MFCD00007693
- EINECS: 220-620-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-25 18:01:19
What is 6-Amino-m-cresol?
Chemical properties
Beige to brown crystal powder
The Uses of 6-Amino-m-cresol
2-Amino-5-methylphenol was used in the synthesis of tridentate Schiff base ligand and novel non-metallocene catalysts with phenoxy-imine ligands.
What are the applications of Application
2-Amino-5-methylphenol is a novel non-metallocene catalyst with phenoxy-imine ligands and used in the synthesis of tridentate Schiff base ligand
General Description
2-Amino-5-methylphenol reacts with bovine hemoglobin to form 2-amino-4,4α-dihydro-4α-7-dimethyl-3H-phenoxazine-3-one, which inhibits the proliferation of Poliovirus in Vero cells. It is converted to dihydrophenoxazinone by purified human hemoglobin.
Purification Methods
Crystallise it from H2O, 50% EtOH, or toluene. [Beilstein
Properties of 6-Amino-m-cresol
| Melting point: | 160-162 °C(lit.) |
| Boiling point: | 229.26°C (rough estimate) |
| Density | 1.0877 (rough estimate) |
| refractive index | 1.5380 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.87±0.10(Predicted) |
| color | Beige to Dark Beige |
| Water Solubility | soluble |
| BRN | 386144 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 2835-98-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 2-amino-5-methyl-(2835-98-5) |
Safety information for 6-Amino-m-cresol
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 6-Amino-m-cresol
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