6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE
- CAS NO.:820231-95-6
- Empirical Formula: C15H20N2O2
- Molecular Weight: 260.33
- MDL number: MFCD09971128
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE?
What are the applications of Application
Sazetidine A dihydrochloride is an agonist of nicotinic acetylcholine receptors
Biological Activity
Subtype-selective α 4 β 2 nicotinic acetylcholine receptor ligand (K i values are 0.26 and 54 nM at α 4 β 2 and α 3 β 4 receptors respectively). May act as a silent desensitizer or as an agonist (EC 50 = 1.1 nM for nAChR-stimulated dopamine release). Exhibits analgesic activity in vivo .
Properties of 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE
storage temp. | Desiccate at +4°C |
form | White to off-white solid. |
Safety information for 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE
Computed Descriptors for 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE
New Products
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