6-(4-Hydroxyphenoxy)hexyl acrylate

CAS NO.：161841-12-9
Empirical Formula: C15H20O4
Molecular Weight: 264.32
MDL number: MFCD09037828
SAFETY DATA SHEET (SDS)
Update Date: 2024-01-09 17:37:02

What is 6-(4-Hydroxyphenoxy)hexyl acrylate?

Chemical properties

off-white powder

The Uses of 6-(4-Hydroxyphenoxy)hexyl acrylate

6-(4-Hydroxyphenoxy)hexyl acrylate is used in organic synthesis and pharmaceutical intermediates.

Preparation

The preparation of 6-(4-Hydroxyphenoxy)hexyl acrylate is as follows:10 g (47.56 mmol) of 4-(6-hydroxyhexyloxy)phenol, 50 ml (551.7 mmol)Methyl acrylate, 0.36g (3.75mmol)Methanesulfonic acid was added to the reaction flask, heated to 40 ° C, reacted for 3 hours, and distilled under reduced pressure.The reaction solution was added to water and stirred with methyl tert-butyl ether.The organic layer was collected, concentrated to dryness, and then filtered with ethyl t-butyl ether and n-heptane.After drying, 12.0 g of an off-white solid was obtained in a yield of 95.5%.The content is ≥98.5%.

storage

Low temperature and keep dry.

Properties of 6-(4-Hydroxyphenoxy)hexyl acrylate

Melting point:	55℃ (water )
Boiling point:	407.6±25.0 °C(Predicted)
Density	1.090±0.06 g/cm3(Predicted)
form	solid
pka	10.33±0.15(Predicted)
color	off-white
InChI	InChI=1S/C15H20O4/c1-2-15(17)19-12-6-4-3-5-11-18-14-9-7-13(16)8-10-14/h2,7-10,16H,1,3-6,11-12H2

Safety information for 6-(4-Hydroxyphenoxy)hexyl acrylate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.