5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER
- CAS NO.：99632-94-7
- Empirical Formula: C15H17N3O3S
- Molecular Weight: 319.38
- MDL number: MFCD00877822
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
![5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER Structural](https://img.chemicalbook.in/CAS/GIF/99632-94-7.gif)
What is 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER?
The Uses of 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER
Ro 19-4603 is a novel benzodiazepine inverse agonist.
What are the applications of Application
RO 19-4603 is an agent that binds with high affinity to GABAA receptors
Definition
ChEBI: Ro 19-4603 is an organonitrogen heterocyclic compound, an organosulfur heterocyclic compound and a tert-butyl ester.
Biological Activity
Benzodiazepine inverse agonist. Binds with high affinity to both diazepam-sensitive (DS) and diazepam-insensitive (DI) GABA A receptors (K i values are ~ 0.2 and ~ 2.6 nM for DS and DI receptors respectively). Antagonizes effects of ethanol on locomotor behavior and suppresses ethanol intake in alcohol-preferring rats.
Properties of 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER
| storage temp. | Store at RT |
| solubility | <31.94mg/ml in ethanol; <31.94mg/ml in DMSO |
Safety information for 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER
Computed Descriptors for 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER
New Products
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