5,5-DIETHYLBARBITURIC ACID SODIUM SALT

Synonym(s):5,5-Diethylbarbituric acid sodium salt;Barbitone;Sodium barbital;Veronal sodium salt

CAS NO.：144-02-5
Empirical Formula: C8H13N2NaO3
Molecular Weight: 208.19
MDL number: MFCD00036203
EINECS: 205-613-9
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:44:01

5,5-DIETHYLBARBITURIC ACID SODIUM SALT Structural

What is 5,5-DIETHYLBARBITURIC ACID SODIUM SALT?

Chemical properties

Bitter crystals or powder.

The Uses of 5,5-DIETHYLBARBITURIC ACID SODIUM SALT

Biological buffer.

Definition

The soluble monosodium salt of barbital. It is a long-acting bar- biturate that depresses most metabolic processes at high doses.

Hazard

Poison; causes marked depression, pro- longed coma, and death; teratogen; questionable carcinogen; tumorigen; neoplastigen; mutagen.

Flammability and Explosibility

Not classified

Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Large doses cause marked depression (sometimes preceded by excitation), prolonged coma, and death. Experimental teratogenic and reproductive effects. Allergic skin reactions may occur on contact. Implicated in development of aplastic anemia. Questionable carcinogin with experimental tumorigenic and neoplastigenic data. A truly habit-forming drug. Other experimental reproductive effects. Mutation data reported. Combustible. When heated to decomposition it emits toxic fumes of NO, and NazO. See also BARBITURATES

Purification Methods

Crystallise it from water (3mL/g) by adding an equal volume of EtOH and cooling to 5o. Dry it under vacuum over P2O5. [Beilstein 24 III/IV 1904.]

Properties of 5,5-DIETHYLBARBITURIC ACID SODIUM SALT

Melting point:	190℃
Density	1.418[at 20℃]
vapor pressure	0.004Pa at 90℃
solubility	H2O: soluble50mg/mL, clear, colorless
form	Solid
color	Bitter crystals or powder
Water Solubility	181.6g/L at 20℃
Merck	13,965
BRN	3921202
CAS DataBase Reference	144-02-5(CAS DataBase Reference)

Safety information for 5,5-DIETHYLBARBITURIC ACID SODIUM SALT

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H371:Specific target organ toxicity, single exposure
Precautionary Statement Codes	P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.