5-NITROISATOIC ANHYDRIDE

CAS NO.：4693-02-1
Empirical Formula: C8H4N2O5
Molecular Weight: 208.13
MDL number: MFCD00023891
EINECS: 225-151-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-06 18:38:04

What is 5-NITROISATOIC ANHYDRIDE?

The Uses of 5-NITROISATOIC ANHYDRIDE

6-Nitro-1H-benzo[d][1,3]oxazine-2,4-dione is a useful research chemical for organic synthesis/bioactive molecule design. 6-Nitro-1H-benzo[d][1,3]oxazine-2,4-dione is also used in the RNA structure probing studies.

Preparation

5-Nitroisatoic anhydride is prepared from 5-nitro indole (9g) by stirring in a 4:1 mixture of CH3CN/H2O for 1 h at 40℃. 1 H NMR (DMSO-d6): δ12.34 (s, Br., 1H), 8.59 (s Hz, 1H), 8.51 (d, J = 7.8 Hz, 1H), 7.31 (d, J = 8.7 Hz, 1H).

Properties of 5-NITROISATOIC ANHYDRIDE

Melting point:	259 °C
Boiling point:	347.31°C (rough estimate)
Density	1.623±0.06 g/cm3 (20 ºC 760 Torr)
refractive index	1.4900 (estimate)
storage temp.	Sealed in dry,Room Temperature
pka	9.29±0.20(Predicted)
CAS DataBase Reference	4693-02-1(CAS DataBase Reference)
EPA Substance Registry System	2H-3,1-Benzoxazine-2,4(1H)-dione, 6-nitro- (4693-02-1)

Safety information for 5-NITROISATOIC ANHYDRIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.