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HomeProduct name list5-Methyltetrahydrofolic acid

5-Methyltetrahydrofolic acid

  • CAS NO.:134-35-0
  • Empirical Formula: C20H25N7O6
  • Molecular Weight: 459.46
  • MDL number: MFCD00900533
  • EINECS: 603-809-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-14 14:09:35
5-Methyltetrahydrofolic acid Structural

What is 5-Methyltetrahydrofolic acid?

Chemical properties

Off-White Solid

The Uses of 5-Methyltetrahydrofolic acid

5-Methyltetrahydrofolic acid is a metabolite of Folic acid; inhibits photosensitization reactions and strand breaks in DNA. 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.

The Uses of 5-Methyltetrahydrofolic acid

5-Methyltetrahydrofolic acid-(glutamic acid-13C5) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.

General Description

5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group.
5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by 13C6 carbon.

Properties of 5-Methyltetrahydrofolic acid

Melting point: >300°C (dec.)
Density  1.62±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  Aqueous Base (Slightly, Sonicated)
form  Solid
pka 3.51±0.10(Predicted)
color  Pale Beige
Stability: Hygroscopic

Safety information for 5-Methyltetrahydrofolic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 5-Methyltetrahydrofolic acid

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