5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE
Synonym(s):5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo[2,3-f]indole hydrochloride hydrate;N-3-Pyridinyl-3,5-dihydro-5-methylbenzo(1,2-b:4,5-b′)dipyrrole-1(2H)carboxamide hydrochloride hydrate
- CAS NO.：158942-04-2
- Empirical Formula: C17H16N4O
- Molecular Weight: 292.34
- MDL number: MFCD00928314
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-06 17:15:43
![5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE Structural](https://img.chemicalbook.in/CAS/GIF/158942-04-2.gif)
What is 5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE?
The Uses of 5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE
SB 206553 Hydrochloride is a 5-HT2 antagonist.
What are the applications of Application
SB 206553 hydrochloride is a selective and potent SR-2B/SR-2C inhibitor
Definition
ChEBI: SB 206553 is a pyrroloindole.
Biological Activity
Potent and selective 5-HT 2B /5-HT 2C receptor antagonist (rat 5-HT 2B pA 2 = 8.89, human 5-HT 2C pK i = 7.92). Displays > 80-fold selectivity over all other 5-HT receptor subtypes and a variety of other receptors (pK i < 6). Centrally active following oral administration in vivo .
Properties of 5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE
| Boiling point: | 575.4±50.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | H2O: 30 mg/mL |
| form | solid |
| pka | 13.50±0.20(Predicted) |
| color | brown |
Safety information for 5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE
Computed Descriptors for 5-METHYL-1-(3-PYRIDYLCARBAMOYL)-1,2,3,5-TETRAHYDROPYRROLO [2,3-F]INDOLE
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