5-METHOXYGRAMINE
Synonym(s):3-(Dimethylaminomethyl)-5-methoxyindole;NSC 88885
- CAS NO.：16620-52-3
- Empirical Formula: C12H16N2O
- Molecular Weight: 204.27
- MDL number: MFCD00005630
- EINECS: 240-669-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 15:13:18
What is 5-METHOXYGRAMINE?
Chemical properties
white to almost white crystalline powder
The Uses of 5-METHOXYGRAMINE
• ;Reactant for preparation of dopamine D2 receptor antagonists1• ;Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction2• ;Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands3• ;Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents4• ;Reactant for preparation of in
The Uses of 5-METHOXYGRAMINE
- Reactant for preparation of dopamine D2 receptor antagonists
- Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction
- Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands
- Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents
- Reactant for preparation of indolylmethanesulfonamide and its methoxy derivatives
Properties of 5-METHOXYGRAMINE
| Melting point: | 123-126 °C (lit.) |
| Boiling point: | 342.77°C (rough estimate) |
| Density | 1.0565 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Refrigerator (+4°C) |
| pka | 16.70±0.30(Predicted) |
| BRN | 170533 |
| CAS DataBase Reference | 16620-52-3(CAS DataBase Reference) |
Safety information for 5-METHOXYGRAMINE
Computed Descriptors for 5-METHOXYGRAMINE
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1,1’-CARBONYLDIIMIDAZOLE DIETHYL AMINOMALONATE HYDROCHLORIDE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![1-[(5-methoxy-1H-indol-3-yl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxylic acid](https://img.chemicalbook.in/StructureFile/ChemBookStructure20/GIF/CB31080343.gif)
![2-ACETYL-8-METHOXY-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE](https://img.chemicalbook.in/StructureFile/ChemBookStructure8/GIF/CB9709135.gif)
![8-BENZYLOXY-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE](https://img.chemicalbook.in/StructureFile/ChemBookStructure8/GIF/CB3262076.gif)
![5-ETHYL-2-(5-METHOXY-1H-INDOL-3-YL)-7-METHYL-1,3-DIAZATRICYCLO[3.3.1.1~3,7~]DECAN-6-ONE](https://img.chemicalbook.in/StructureFile/ChemBookStructure9/GIF/CB0493130.gif)
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