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HomeProduct name list5-Hydroxymethylpyrrolidin-2-one

5-Hydroxymethylpyrrolidin-2-one

Synonym(s):D-Pyroglutaminol

  • CAS NO.:66673-40-3
  • Empirical Formula: C5H9NO2
  • Molecular Weight: 115.13
  • MDL number: MFCD00077791
  • EINECS: 626-701-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-01-18 17:18:22
5-Hydroxymethylpyrrolidin-2-one Structural

What is 5-Hydroxymethylpyrrolidin-2-one?

Chemical properties

(R)-5-(Hydroxymethyl)-2-pyrrolidinone is White Powder

The Uses of 5-Hydroxymethylpyrrolidin-2-one

Serves as a building block in the synthesis of diphthamide

The Uses of 5-Hydroxymethylpyrrolidin-2-one

(R)-5-(Hydroxymethyl)-2-pyrrolidinone is a 2-pyrrolidone derivative for therapeutic use as prostanoid receptor agonist.

The Uses of 5-Hydroxymethylpyrrolidin-2-one

Serves as a building block in the synthesis of diphthamide.

Properties of 5-Hydroxymethylpyrrolidin-2-one

Melting point: 83-85 °C(lit.)
Boiling point: 147-149 °C0.06 mm Hg(lit.)
Density  1.1808 (rough estimate)
refractive index  -31 ° (C=5, EtOH)
Flash point: 147-149°C/0.06m
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Chloroform, Dimethylformamide, Water
form  Crystalline Powder or Flakes
pka 14.35±0.10(Predicted)
color  White to yellow
optical activity [α]20/D 31°, c = 5 in ethanol
BRN  5728422
CAS DataBase Reference 66673-40-3(CAS DataBase Reference)

Safety information for 5-Hydroxymethylpyrrolidin-2-one

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 5-Hydroxymethylpyrrolidin-2-one

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