5-Hydroxymethylpyrrolidin-2-one
Synonym(s):D -Pyroglutaminol
- CAS NO.：66673-40-3
- Empirical Formula: C5H9NO2
- Molecular Weight: 115.13
- MDL number: MFCD00077791
- EINECS: 626-701-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-01-18 17:18:22
What is 5-Hydroxymethylpyrrolidin-2-one?
Chemical properties
(R)-5-(Hydroxymethyl)-2-pyrrolidinone is White Powder
The Uses of 5-Hydroxymethylpyrrolidin-2-one
Serves as a building block in the synthesis of diphthamide
The Uses of 5-Hydroxymethylpyrrolidin-2-one
(R)-5-(Hydroxymethyl)-2-pyrrolidinone is a 2-pyrrolidone derivative for therapeutic use as prostanoid receptor agonist.
The Uses of 5-Hydroxymethylpyrrolidin-2-one
Serves as a building block in the synthesis of diphthamide.
Properties of 5-Hydroxymethylpyrrolidin-2-one
| Melting point: | 83-85 °C(lit.) |
| Boiling point: | 147-149 °C0.06 mm Hg(lit.) |
| Density | 1.1808 (rough estimate) |
| refractive index | -31 ° (C=5, EtOH) |
| Flash point: | 147-149°C/0.06m |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, Dimethylformamide, Water |
| form | Crystalline Powder or Flakes |
| pka | 14.35±0.10(Predicted) |
| color | White to yellow |
| optical activity | [α]20/D 31°, c = 5 in ethanol |
| BRN | 5728422 |
| CAS DataBase Reference | 66673-40-3(CAS DataBase Reference) |
Safety information for 5-Hydroxymethylpyrrolidin-2-one
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-Hydroxymethylpyrrolidin-2-one
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