5-FLUORO-DL-TRYPTOPHAN
- CAS NO.：154-08-5
- Empirical Formula: C11H11FN2O2
- Molecular Weight: 222.22
- MDL number: MFCD00005649
- EINECS: 205-822-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 5-FLUORO-DL-TRYPTOPHAN?
Chemical properties
light beige powder
The Uses of 5-FLUORO-DL-TRYPTOPHAN
A metabolic antagonist of tryptophan
Definition
ChEBI: A non-proteinogenic alpha-amino acid that is tryptophan in which the hydrogen at position 5 on the indole ring is replaced by a fluoro group.
Purification Methods
Recrystallise it from EtOH, aqueous EtOH or AcOH. Also purify it by passage through a Dowex AG1x2 (acetate form) column and recrystallise the L-enantiomer (from enzymic enrichment) from H2O/EtOH, m 158-163o(dec), [] D -8.3o (c 2.5, N NaOH). [Coy et al. Biochemistry 13 3550 1974, Beilstein 22/14 V 116.]
Properties of 5-FLUORO-DL-TRYPTOPHAN
| Melting point: | 265 °C (dec.)(lit.) |
| Boiling point: | 450.7±45.0 °C(Predicted) |
| Density | 1.2556 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| form | powder |
| pka | 2.21±0.10(Predicted) |
| color | white |
| BRN | 22753 |
| CAS DataBase Reference | 154-08-5(CAS DataBase Reference) |
Safety information for 5-FLUORO-DL-TRYPTOPHAN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 5-FLUORO-DL-TRYPTOPHAN
| InChIKey | INPQIVHQSQUEAJ-UHFFFAOYSA-N |
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