5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
- CAS NO.:144625-67-2
- Empirical Formula: C19H26FN3O5S
- Molecular Weight: 427.49
- MDL number: MFCD00912900
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE?
The Uses of 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
GR 125487 Sulfamate is potent, selective 5-HT4 antagonist; active in vivo.
Biological Activity
Potent and selective 5-HT 4 receptor antagonist (K i = 0.19 nM for porcine 5-HT 4 ). Centrally active following systemic administration in vivo .
Properties of 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
Melting point: | 118-120℃ |
Boiling point: | 613.4±65.0 °C(Predicted) |
Density | 1.313±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | H2O: ~14 mg/mL at 60 °C, soluble |
form | solid |
pka | 11.22±0.40(Predicted) |
color | off-white |
Safety information for 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
Computed Descriptors for 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
5-FLUOROINDOLE-3-CARBOXALDEHYDE
[1-(2-aminoethyl)-4-piperidinyl]methanol
5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
5-FLUORO-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER
5-FLUOROINDOLE-3-CARBOXYLIC ACID
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