5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
- CAS NO.：144625-67-2
- Empirical Formula: C19H26FN3O5S
- Molecular Weight: 427.49
- MDL number: MFCD00912900
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
![5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE Structural](https://img.chemicalbook.in/CAS/GIF/144625-67-2.gif)
What is 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE?
The Uses of 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
GR 125487 Sulfamate is potent, selective 5-HT4 antagonist; active in vivo.
Biological Activity
Potent and selective 5-HT 4 receptor antagonist (K i = 0.19 nM for porcine 5-HT 4 ). Centrally active following systemic administration in vivo .
Properties of 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
| Melting point: | 118-120℃ |
| Boiling point: | 613.4±65.0 °C(Predicted) |
| Density | 1.313±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | H2O: ~14 mg/mL at 60 °C, soluble |
| form | solid |
| pka | 11.22±0.40(Predicted) |
| color | off-white |
Safety information for 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
Computed Descriptors for 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
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![[1-(2-aminoethyl)-4-piperidinyl]methanol](https://img.chemicalbook.in/CAS/GIF/129999-62-8.gif)
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