5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
- CAS NO.:144625-67-2
- Empirical Formula: C19H26FN3O5S
- Molecular Weight: 427.49
- MDL number: MFCD00912900
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE?
The Uses of 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
GR 125487 Sulfamate is potent, selective 5-HT4 antagonist; active in vivo.
Biological Activity
Potent and selective 5-HT 4 receptor antagonist (K i = 0.19 nM for porcine 5-HT 4 ). Centrally active following systemic administration in vivo .
Properties of 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
Melting point: | 118-120℃ |
Boiling point: | 613.4±65.0 °C(Predicted) |
Density | 1.313±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | H2O: ~14 mg/mL at 60 °C, soluble |
form | solid |
pka | 11.22±0.40(Predicted) |
color | off-white |
Safety information for 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
Computed Descriptors for 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
5-FLUOROINDOLE-3-CARBOXALDEHYDE
[1-(2-aminoethyl)-4-piperidinyl]methanol
5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
5-FLUORO-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER
5-FLUOROINDOLE-3-CARBOXYLIC ACID
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