5-Chloro-3-pyridinol
Synonym(s):5-Chloro-3-pyridinol
- CAS NO.：74115-12-1
- Empirical Formula: C5H4ClNO
- Molecular Weight: 129.54
- MDL number: MFCD00006379
- EINECS: 277-727-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-25 10:25:51
What is 5-Chloro-3-pyridinol?
Chemical properties
orange-brown to brown crystalline powder
The Uses of 5-Chloro-3-pyridinol
5-Chloro-3-hydroxypyridine is used in the preparation of 4-(5-chloropyridin-3-yloxy)isoquinoline
Definition
ChEBI: 5-Chloropyridin-3-ol is a hydroxypyridine.
General Description
5-Chloro-3-hydroxypyridine undergoes Suzuki-Miyaura cross-coupling with 3-pyridylboronic acid in the presence of Pd catalyst to yield hydroxybiphenyls.
Properties of 5-Chloro-3-pyridinol
| Melting point: | 160-162 °C (lit.) |
| Boiling point: | 324.7±22.0 °C(Predicted) |
| Density | 1.2309 (rough estimate) |
| refractive index | 1.4510 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 8.37±0.10(Predicted) |
| form | powder to crystal |
| color | Light yellow to Brown |
| Water Solubility | Soluble in water. |
| BRN | 1422550 |
| CAS DataBase Reference | 74115-12-1(CAS DataBase Reference) |
Safety information for 5-Chloro-3-pyridinol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-Chloro-3-pyridinol
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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