5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
- CAS NO.：28480-70-8
- Empirical Formula: C9H9ClO2
- Molecular Weight: 184.62
- MDL number: MFCD00191920
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:34
What is 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE?
The Uses of 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
5′-Chloro-2′-hydroxy-4′-methylacetophenone (5-chloro-2-hydroxy-4-methylacetophenone) may be used in the preparation of the following:
- chalcones, required for the synthesis of novel pyrazoline derivatives
- 5′-chloro-2′-hydroxy-4′-methyl-3-(2′′-thienyl)acrylophenone
- 6-chloro-3-hydroxy-7-methyl-2-(2-thienyl)-4H-chromen-4-one, a complexing agent used for the spectrophotometric determination of vanadium(V)
Preparation
Preparation by reaction of acetic acid on 4-chloro-3- methylphenol with boron trifluoride at 70–100° (80–85%).
General Description
5′-chloro-2′-hydroxy-4′-methylacetophenone (5-Chloro-2-hydroxy-4-methylacetophenone) is a hydroxylated aromatic acetophenone. Its iodination by pyridinium iodochloride has been reported to afford 5-chloro-2-hydroxy-3-iodo-4-methylacetophenone.
Properties of 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
| Melting point: | 70-73 °C(lit.) |
| Boiling point: | 137 °C / 15mmHg |
| Density | 1.250±0.06 g/cm3(Predicted) |
| form | powder to crystal |
| pka | 9.84±0.23(Predicted) |
| color | White to Light yellow |
| CAS DataBase Reference | 28480-70-8(CAS DataBase Reference) |
Safety information for 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE manufacturer
BASR Fine Chemicals Pvt. Ltd.
1Y
Phone:+91-9848230391
Whatsapp: +91-9848230391
product: 5'-Chloro-2'-hydroxy-4'-methylacetophenone 28480-70-8 98%
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