5'-Chloro-2'-hydroxy-3'-nitroacetophenone

CAS NO.：84942-40-5
Empirical Formula: C8H6ClNO4
Molecular Weight: 215.59
MDL number: MFCD00191921
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 5'-Chloro-2'-hydroxy-3'-nitroacetophenone?

The Uses of 5'-Chloro-2'-hydroxy-3'-nitroacetophenone

5′-Chloro-2′-hydroxy-3′-nitroacetophenone may be used for the synthesis of 6-chloro-8-nitro-4-oxo-4H-chromene-3-carbaldehyde.

Preparation

Preparation by reaction of nitric acid on 5-chloro-2- hydroxyacetophenone in acetic acid at r.t.

General Description

5′-Chloro-2′-hydroxy-3′-nitroacetophenone (5-chloro-3-nitro-2-hydroxyacetophenone) is a nitro derivative of ortho-hydroxy aryl ketone. Its crystal structure has been studied by X-ray diffraction. It forms complex with 2-aminobenzoic acid (anthranilic acid), in which the nitro group is turned by approximately 40°C.

Properties of 5'-Chloro-2'-hydroxy-3'-nitroacetophenone

Melting point:	132-135 °C(lit.)
form	powder to crystal
color	White to Yellow to Orange
CAS DataBase Reference	84942-40-5(CAS DataBase Reference)

Safety information for 5'-Chloro-2'-hydroxy-3'-nitroacetophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.