5'-BROMO-2'-HYDROXYPROPIOPHENONE 97

CAS NO.：17764-93-1
Empirical Formula: C9H9BrO2
Molecular Weight: 229.07
MDL number: MFCD00218577
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 5'-BROMO-2'-HYDROXYPROPIOPHENONE 97?

Preparation

Preparation by Fries rearrangement of 4-bromophenyl propionate with aluminium chloride at 165° for 1 h (97%), at 150–160° for 30 min or at 120° for 30–40 min (80%)
Preparation by bromination of o-hydroxypropiophenone with bromine in 80% aqueous acetic acid at r.t. (66%)
Also obtained by acylation of p-bromophenol with propionic acid in the presence of boron trifluoride in a sealed tube at 120° for 1 h (59%).

Properties of 5'-BROMO-2'-HYDROXYPROPIOPHENONE 97

Melting point:	78-79°C
Boiling point:	156°C/21mmHg(lit.)
Density	1.506±0.06 g/cm3(Predicted)
form	powder to crystal
pka	7.68±0.48(Predicted)
color	White to Light yellow to Light orange

Safety information for 5'-BROMO-2'-HYDROXYPROPIOPHENONE 97

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H301:Acute toxicity,oral H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.