5-Amino-2-methylbenzenesulfonamide
- CAS NO.：6973-09-7
- Empirical Formula: C7H10N2O2S
- Molecular Weight: 186.23
- MDL number: MFCD06681071
- EINECS: 691-180-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-22 14:21:17
What is 5-Amino-2-methylbenzenesulfonamide?
Chemical properties
White to Light yellow to Light orange powder to crystal.
The Uses of 5-Amino-2-methylbenzenesulfonamide
5-Amino-2-methylbenzenesulfonamide is an intermediate for the synthesis of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
Properties of 5-Amino-2-methylbenzenesulfonamide
| Melting point: | 163-164℃ |
| Boiling point: | 421.5±55.0 °C(Predicted) |
| Density | 1.359±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 10.43±0.60(Predicted) |
| color | Pale Beige |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 6973-09-7(CAS DataBase Reference) |
Safety information for 5-Amino-2-methylbenzenesulfonamide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 5-Amino-2-methylbenzenesulfonamide
| InChIKey | KTPBKMYOIFHJMI-UHFFFAOYSA-N |
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