5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione
- CAS NO.:144809-28-9
- Empirical Formula: C19H18N2O3S
- Molecular Weight: 354.42
- MDL number: MFCD06411145
- EINECS: 604-444-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-06 17:55:34
What is 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione?
Chemical properties
White Solid
The Uses of 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione
A novel intermediate of Pioglitazone (P471000).
The Uses of 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione (Pioglitazone EP Impurity B) is a novel intermediate of Pioglitazone (P471000).
Properties of 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione
Melting point: | 156-159°C |
Density | 1.301±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly) |
form | Solid |
pka | 7.26±0.20(Predicted) |
color | White to Pale Yellow |
CAS DataBase Reference | 144809-28-9(CAS DataBase Reference) |
Safety information for 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione
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Hydroxypioglitazone
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4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyaldehyde
5-(4-Fluorobenzyl)-2,4-thiazolidinedione
a-[(Aminocarbonyl)thio]-4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzenepropanoic Acid Ethyl Ester
2-Ethylpyridine
4-Ethylpyridine
3-Ethylpyridine
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