Hydroxypioglitazone
- CAS NO.：146062-44-4
- Empirical Formula: C19H20N2O4S
- Molecular Weight: 372.44
- MDL number: MFCD00916074
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is Hydroxypioglitazone?
Description
Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor γ (PPARγ) agonist pioglitazone (Item Nos. 71745 | 22263 | 10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to PPARγ (Ki = 1.2 μM) and activates PPARγ in a time-resolved FRET (TR-FRET) assay (EC50 = 2.1 μM).
Chemical properties
Off-White Solid
The Uses of Hydroxypioglitazone
A metabolite of Pioglitazone (P471000).
What are the applications of Application
Hydroxy Pioglitazone (M-IV) is a pioglitazone metabolite
Definition
ChEBI: Hydroxypioglitazone is a member of the class of thiazolidenediones that is the hydroxy derivative of pioglitazone. It has a role as a human xenobiotic metabolite. It is a member of thiazolidinediones, a member of pyridines and an aromatic ether. It is functionally related to a pioglitazone.
Properties of Hydroxypioglitazone
| Melting point: | 157-1580C |
| Boiling point: | 627.6±55.0 °C(Predicted) |
| Density | 1.325±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| form | Solid |
| pka | 6.35±0.50(Predicted) |
| color | White to Off-White |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 146062-44-4 |
Safety information for Hydroxypioglitazone
Computed Descriptors for Hydroxypioglitazone
Hydroxypioglitazone manufacturer
Varanous Labs Pvt Ltd
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![a-[(Aminocarbonyl)thio]-4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzenepropanoic Acid Ethyl Ester](https://img.chemicalbook.in/CAS/GIF/868754-41-0.gif)
![2-[2-(4-BroMophenoxy)ethyl]-5-ethylpyridine](https://img.chemicalbook.in/CAS/GIF/669716-58-9.gif)
![4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyaldehyde](https://img.chemicalbook.in/CAS/GIF/114393-97-4.gif)
You may like
-
146062-44-4 Pioglitazone metabolite MIV 98%View Details
146062-44-4 -
2033-24-1 98%View Details
2033-24-1 -
1975-50-4 98%View Details
1975-50-4 -
2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 221615-75-4 98%View Details
221615-75-4 -
61397-56-6 CIS BROMO BENZOATE 98%View Details
61397-56-6 -
14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+View Details
14714-50-2 -
118753-70-1 98+View Details
118753-70-1